zěn me gǎo de
How did it happen?
What's wrong?; What went wrong?; What's up?
怎
zěn
how
么
me
suffix, used to form interrogative 什麼|什么[shen2 me5], what?, indefinite 這麼|这么[zhe4 me5] thus, etc
搞
gǎo
to do
的
de
of; ~'s (possessive particle)